Barr Lab News

February 2021

The Barr lab has been making lemonade out of lemons this past pandemic year. In March 2020, we quickly locked down thanks to our super lab manager Gloria Androwski and the dauer worms. During work from home, we focused on writing manuscripts and fellowships. Over the summer, we slowly returned to the lab and now continue to work at 50% capacity. As a result of our quick strategic planning and teamwork, we published many exciting new stories. Check them out!

Juan Wang and Inna Nikonorova discovered that male cilia release PKD-::GFP carrying-EVs in response to mechanical pressure and that EVs are targeted to the hermaphrodite vulva during mating.

Jonathon Walsh and Olivier Boivin penned a hybrid review-research paper on male mating behavior for a special issue on Brenner and Sulston.

Kade Power, Shilpa Akella and Bob O’Hagan and his undergraduate screen team published their paper on identifying regulators of ciliary stability and degeneration. Kade continues to probe the mechanism by which the NEKL-4 kinase regulates hyper-glutamylation induced ciliary degeneration.

Shilpa Akella wrote an epic review on the role of the tubulin code in extracellular vesicle releasing neurons.